How to Solve the Protein Folding Problem: AlphaFold2

A deeper look at AlphaFold2 and its neural architecture

Illustration of protein sequence to shape. In white the original protein, in rainbow the AlphaFold predicted protein [blue=highest confidence, red=lowest confidence] (Illustration by the author)

In this series of articles, I will go through protein folding and deep learning models such as AlphaFold, OmegaFold, and ESMFold. We will start with AlphaFold2!

Introduction